Red Sox DH Ortiz replaced in 5th inning

BOSTON (AP) Designated hitter David Ortiz has left in the fifth inning of Boston's game against Philadelphia because of right calf tightness.

The 39-year-old slugger connected for a two-run shot against Jerad Eickhoff in the first, lifting the Red Sox to a 2-0 lead. It was his 200th homer at Fenway Park and No. 497 for his career overall.

Ortiz added a sacrifice fly in the second on Sunday.