NFL Opening Night

Grammy award winners Kelly Clarkson, John Mellencamp and Faith Hill provided the pregame entertainment.

Seven months after winning Super Bowl XLI, the Indianapolis Colts were fired up to begin their title defense.

The first touchdown of the season was scored by Marvin Harrison, who hauled in a 27-yard pass from Peyton Manning.

Peyton Manning was in midseason form and led the Colts to 31 unanswered points in the second half.

Making his first career start, Joseph Addai rushed for 118 yards, including a 2-yard TD plunge in the third quarter.

Reggie Bush was held to 45 total yards on 16 touches.

Matt Giordano's 83-yard interception return capped the opening-night rout.

Saints QB Drew Brees finished 27-of-40 for 183 yards and two interceptions.

Brees and Manning exchanged pleasantries after the game.