Ten Can't-Miss NFL Games of 2008

Ten Can't-Miss NFL Games of 2008

Vikings at Packers, Sept. 8

Joe Murphy/Getty Images

This will be the first Packers game without Brett Favre since 1991.

Lions at 49ers, Sept. 21

Gregory Shamus/Getty Images

The Mike Martz Bowl. The new offensive coordinator for the 49ers will be looking to run up the score on his former team.

Patriots at Chargers, Oct. 12

Damian Strohmeyer/SI

A rematch of the AFC championship game. The Patriots have eliminated the Chargers from the playoffs the past two years.

Chargers at Saints (in London), Oct. 26

Paul Childs/ POOL/Getty Images, John W. McDonough/SI, Al Tielemans/SI

Unlike last year's rain-soaked stinker between the Dolphins and Giants, this year's game at Wembley Stadium is a possible Super Bowl preview.

Cowboys at Giants, Nov. 2

Damian Strohmeyer/SI, Al Tielemans/SI, John W. McDonough/SI

The first of two games between the defending NFC East champ and the defending Super Bowl champ.

Patriots at Colts, Nov. 2

Al Tielemans/SI

The NFL's best rivalry resumes. The Colts will be seeking payback after the Pats came back from 10 down to win 24-20 in Week 9.

Colts at Chargers, Nov. 23

John Biever/SI

The Chargers have had the Colts' number, beating them twice last season.

Colts at Browns, Nov. 30

AP

Remember how the Colts tanked it against the Titans, inadvertently causing the Browns to miss the playoffs? Cleveland sure does.

Dolphins at Bills, Dec. 7

Dave Sandford/Getty Images, David Bergman/SI, Eliot J. Schechter/Getty Images

The NFL invades CFL territory when the Bills make their regular-season debut in Toronto.

Seahawks at Cardinals, Dec. 28

Stephen Dunn/Getty Images

The Seahawks final regular-season game could possibly be Mike Holmgren's final game in the NFL.