The Rams have five picks remaining in the NFL draft, including one each in the second and third rounds on Friday night.
After selecting Gurley with the 10th pick, coach Jeff Fisher said the Georgia star running back was a special talent. Gurley, the first running back taken in the first round since 2012, is coming off left knee surgery and the Rams (6-10) don't know if he'll be ready for the season opener.
St. Louis has just two offensive line starters back, tackle Greg Robinson and guard Rodger Saffold. Passing up on O-line help in the first round could accelerate negotiations to re-sign tackle Joe Barksdale, an unrestricted free agent.