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Report: Bills RB LeSean McCoy (hamstring) will be ready for Week 1

Buffalo Bills running back LeSean McCoy left practice Tuesday with a hamstring injury.

Buffalo Bills running back LeSean McCoy left practice Tuesday with a hamstring injury, but an MRI confirmed he would be ready to play by the Bills' season opener against the Colts, Ian Rapoport of reports

McCoy grabbed his leg during red zone drills and left the field accompanied by trainers.

Bills coach Rex Ryan said in a press conference after practice that McCoy would have an MRI, and that the “next man up will have to step up” for Buffalo, whose running back corps have been depleted by injuries in the early weeks of the season. “It's intact, not off the bone, so that's positive,” Ryan told media. “Hoping it's not a pull, just a strain.”

McCoy, 27, is in his first year with the Bills after being traded from Philadelphia in the off-season for linebacker Kiko Alonso. He ran for 1,319 yards and five touchdowns with the Eagles in 2014 and has averaged 4.6 yards per carry in his six-year career, scoring 54 total touchdowns. He is expected to anchor the Buffalo ground game this season.

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Ryan also said Bills rookie running back Karlos Williams would be out for two weeks. Williams was reportedly likely to miss multiple weeks with an undisclosed injury.

Bills running backs Fred Jackson, Bryce Brown and Boobie Dixon have all missed time with injuries already during training camp.

The Bills reportedly considered signing former Ravens running back Ray Rice in the wake of McCoy's injury. 

Jeremy Woo