Coach Rex Ryan doesn't expect the injury to prevent McCoy from playing Sunday, when the Bills (1-0) host the AFC East rival New England Patriots (1-0). Ryan backed off on McCoy's practice time Thursday after the player complained his hamstring felt tight.
McCoy missed Buffalo's final three preseason games after straining the hamstring Aug. 18.
McCoy acknowledged feeling rusty in Buffalo's 27-14 season-opening win against Indianapolis last weekend. He had 17 carries for 41 yards and three catches for 46 yards.
Starting safety Corey Graham is scheduled to have tests Friday to determine whether he'll be cleared to play after sustaining a concussion last weekend.
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