The rookie third-round pick had started eight games this season.
Right tackle Seantrel Henderson is probable after missing the past two weeks with an illness, but his status as a starter will be a game-time decision. Backup Jordan Mills replaced Henderson last week against Houston and worked with the starting unit during the open portions of practice during the week.
Coach Rex Ryan says Henderson improved throughout the week and both players are likely to play against Philadelphia.
Cornerback Stephon Gilmore (shoulder), linebacker Nigel Bradham (ankle), cornerback Ron Brooks (shoulder, concussion), running back Karlos Williams (shoulder), safety Aaron Williams (neck) and linebacker Tony Steward (back) are out.