Freeman gets the start for the Colts
The Carolina Panthers are missing three starters as they try to secure the No. 1 seed in the NFC playoffs
Wide receiver Ted Ginn Jr. (knee), running back Jonathan Stewart (foot) and safety Kurt Coleman (foot) are inactive. Stewart misses his third straight game. Ginn and Coleman were injured in last week's loss at Atlanta that ended Carolina's bid for a perfect regular season.
Cameron Artis-Payne is expected to get most of the carries with Stewart's primary backup Fozzy Whittaker also out. Devin Funchess starts for Ginn and Tre Boston starts for Coleman.
The Panthers will clinch home-field advantage throughout the NFC playoffs with a win over Tampa Bay or if Arizona loses to Seattle.
Here are the inactives:
TAMPA BAY AT CAROLINA
Buccaneers: QB Ryan Griffin, RB Mike James, LB Darius Eubanks, DE Kourtnei Brown, OT Gosder Cherilus, TE Tevin Westbrook, TE Brandon Myers.
Panthers: WR Ted Ginn Jr., RB Jonathan Stewart, FS Kurt Coleman, RB Fozzy Whittaker, WR Kevin Norwood, DE Ryan Delaire, LB David Mayo.
SEATTLE AT ARIZONA
Seahawks: CB Tye Smith, RB Marshawn Lynch, S Kam Chancellor, G J.R. Sweezy, OT Russell Okung, TE Luke Willson, DT A.J. Francis.
Cardinals: QB Matt Barkley, CB Corey White, OLB Markus Golden, LB Shaq Riddick, OT D.J. Humphries, NT Xavier Williams, DT Josh Mauro.
SAN DIEGO AT DENVER
Chargers: WR Stevie Johnson, CB Jason Verrett, TE Asante Cleveland, ILB Kavell Conner, G Orlando Franklin, T King Dunlap TE, Sean McGrath.
Broncos: QB Trevor Siemian, WR Bubba Caldwell, S/KR Omar Bolden, CB Lorenzo Doss, C Sam Brenner, G Robert Myers, NT Darius Kilgo.
ST. LOUIS AT SAN FRANCISCO
Rams: RB Todd Gurley, DT Louis Trinca-Pasat, OL Andrew Donnal, OL Brian Folkerts, OL Isaiah Battle, DB Tye Hill.
49ers: WR DeAndrew White, S Jaquiski Tartt, G Brandon Thomas, C Marcus Martin, TE Je'Ron Hamm, DT Quinton Dial, LB Corey Lemonier.
OAKLAND AT KANSAS CITY
Raiders: CB Dexter McDonald, CB SaQwan Edwards, LB John Lotulelei, S Tevin McDonald, OL Matt McCants, WR Rod Streater, TE Cabe Holmes.
Chiefs: QB Aaron Murray, S Husain Abdullah, LB Justin Houston, OT Jah Reid, DT David King, DL Rakeem Nunez-Roches.
TENNESSEE AT INDIANAPOLIS
Titans: QB Marcus Mariota, WR Kendall Wright, WR Damaris Johnson, CB Blidi Wreh-Wilson, S Josh Aubrey, OT Taylor Lewan and DE Ropati Pitoitua
Colts: QB Stephen Morris, QB Matt Hasselbeck, QB Andrew Luck, S Winston Guy, LB Sio Moore, LB Trent Cole, DT Kelcy Quarles.
NEW ORLEANS AT ATLANTA
Saints: WR Marques Colston, QB Garrett Grayson, LB Dannell Ellerbe, DT Kaleb Eullis, OT Terron Armstead, OT Andrus Peat, TE Josh Hill, TE Rashaun Allen
Falcons: RB Tevin Coleman, S Robenson Therezie, LB Tyler Starr, OG Ben Garland, OT Bryce Harris, TE D.J. Tialavea, DE Malliciah Goodman.
JACKSONVILLE AT HOUSTON
Jaguars: RB T.J. Yeldon, CB Demetrius McCray, LB Telvin Smith, OT Jermey Parnell, WR Bryan Walters, TE Nic Jacobs, DE Chris Smith.
Texans: WR Cecil Shorts, S Rahim Moore, ILB Justin Tuggle, G Oday Aboushi, TE Garrett Graham, OLB Jadeveon Clowney, DE Jeoffrey Pagan.
WASHINGTON AT DALLAS
Redskins: LB Perry Riley Jr., T Trent Williams, DE Jason Hatcher, S Dashon Goldson, QB Robert Griffin III, RB Matt Jones, CB Quinton Dunbar.
Cowboys: LB Sean Lee, CB Morris Claiborne, G La'el Collins, QB Jameill Showers, WR Rodney Smith, T Chaz Green, WR Vince Mayle.
DETROIT AT CHICAGO
Lions: WR Corey Fuller, RB George Winn, C Braxton Cave, DT Khyri Thornton, OT Corey Robinson, DT Gabe Wright, DE Jason Jones.
Bears: WR Eddie Royal, CB Jacoby Glenn, C Hroniss Grasu, OT Tayo Fabuluje, TE Zach Miller, DE Jarvis Jenkins, DL Terry Williams.
BALTIMORE AT CINCINNATI
Ravens: QB Jimmy Clausen, CB Tray Walker, CB Sheldon Price, CB Jumal Rolle, DB Jermaine Whitehead, LB Albert McClellan, DE Kapron Lewis-Moore.
Bengals: QB Andy Dalton, WR Mario Alford, OT Eric Winston, HB Ryan Hewitt, DT Marcus Hardison, DT Pat Sims, DE Will Clarke.
NEW YORK JETS AT BUFFALO
Bills: QB Josh Johnson, WR Dez Lewis, RB LeSean McCoy, LB Nigel Bradham, DE Max Valles, DT T.J. Barnes, DE Lavar Edwards.
Jets: QB Bryce Petty, RB Bilal Powell, CB Dee Milliner, S Dion Bailey, LB Taiwan Jones, RG Dakota Dozier and LB Josh Martin.
NEW ENGLAND AT MIAMI
Dolphins: QB Logan Thomas, CB Jamar Taylor, C Mike Pouncey, LB Jelani Jenkins, G Shelley Smith, T Ja'Wuan James, DT Earl Mitchell.
Patriots: DE Chandler Jones, WR Julian Edelman, LB Dont'a Hightower, T Sebastian Vollmer, DL Sealver Siliga, DB Justin Coleman, LB Jonathan Freeny.
PITTSBURGH AT CLEVELAND
Steelers: QB Mike Vick, WR Sammie Coates, CB Droan Grant, RB Jordan Todman, LB L.J. Fort, OT Byron Stingily, DE L.T. Walton.
Browns: QB Johnny Manziel, WR Marlon Moore, DB Tramon Williams, RB Glenn Winston, DB Charles Gaines, WR Dwayne Bowe, LB Armonty Bryant.
PHILADELPHIA AT NEW YORK GIANTS
Eagles: QB Thad Lewis, WR Jonathan Krause, WR Seyi Ajirotutu, CB Byron Maxwell, DB Jaylen Watkins, LB Steven Means, G/T Tanner Hawkinson.
Giants: WR Dwayne Harris, WR Geremy Davis, S Cooper Taylor, S Craig Dahl, T Emmett Cleary, DE Kerry Wynn, T Marshall Newhouse.
AP NFL website: www.pro32.ap.org and http://twitter.com/AP-NFL