David de Gea was substituted for during Spain's Euro 2020 qualifier with Sweden on Tuesday, leaving with a suspected groin injury.
De Gea, who has struggled to dislodge Chelsea stopper Kepa Arrizabalaga as La Roja's No. 1 goalkeeper recently, was finally given a chance to re-stake his claim for a regular spot in Robert Moreno's side following Kepa's error against Noway last week.
However the Manchester United star appeared to hold his groin and dropped to the ground in pain after clearing a ball. He was replaced by Arrizabalaga in the 60th minute of the 1-1 draw, which cemented Spain's place at Euro 2020, but managed to walk from the field.
Ole Gunnar Solskjaer is still hoping to welcome a number of first-team stars back for United's clash with Liverpool on Sunday. Anthony Martial, Paul Pogba, Aaron Wan-Bissaka, Victor Lindelof and Luke Shaw are all expected to be available, but De Gea's injury could leave the Red Devils without one of their top performers. It is not yet clear whether or not De Gea will be fit to face the Premier League leaders.
Man United is already five points off the pace in the race for Champions League qualification, sitting in 12th in the Premier League. Solskjaer's side has nine points, having won just two of its eight games so far this season.