Federer, Serena highlight Centre Court play on Day 5

LONDON (AP) After a three-year absence from Wimbledon, Juan Martin del Potro is making another strong run at a Grand Slam.

Del Potro, the 2009 U.S. Open champion who has undergone three surgeries on his left wrist since 2014, beat fourth-seeded Stan Wawrinka 3-6, 6-3, 7-6 (2), 6-3 on Friday to reach the third round on another rainy day at the All England Club.

Wawrinka, a two-time Grand Slam champion, is the highest seeded man eliminated so far.

The match was played with the retractable roof closed over Centre Court, with play on the outside courts delayed and interrupted by scattered rain.

This is del Potro's first appearance at Wimbledon since 2013, when he reached the semifinals, and his first at any major since the 2014 Australian Open.

The 27-year-old Argentine, who had played just one match against a top-10 player since November 2013, showed flashes of the explosive game that made him one of the most feared men in tennis.

After dropping the first set, del Potro lifted his game and took a 4-1 lead in the second set to take control. He relied on the low, flat and deep forehand that is considered one of the best shots in the game.

Wawrinka, who has reached the quarterfinals twice at Wimbledon, was far from his best, with more unforced errors than winners - 48 to 47. Even del Potro's stats weren't great: 23 winners and 25 unforced errors. But he managed four breaks of serve, compared to three for Wawrinka.

While rain delayed early matches on the outside courts Friday, Serena Williams and Roger Federer were also playing on Centre Court.

Six-time women's winner Williams was facing fellow American Christina McHale in a second-round match, with seven-time men's champion Federer up third against British player Daniel Evans in the third round.