Friday October 9th, 2015

Bills running backs LeSean McCoy and Karlos Williams have been ruled out for Sunday’s game against the Titans, with receiver Sammy Watkins listed as questionable.

Buffalo coach Rex Ryan announced the news Friday. Boobie Dixon will start at running back for the Bills.

Williams, a rookie, suffered a concussion in last week’s game against the Giants and has yet to be cleared through the NFL’s concussion protocol. McCoy has battled a hamstring injury since training camp and has not played since Week 3 against the Dolphins. He told reporters he had a Grade 2 hamstring pull and will miss three to four weeks.

Watkins also sat out last week’s game against New York with a calf injury, and whether he will play will be a game-time decision. He was limited in practice Friday.

Ryan was optimistic about his receiver’s progression in the recovery process, and hoped to have him available against Tennessee. Watkins said he was still unsure, but if it was an “emergency” situation, he thought he would be able to play.

In three games, McCoy has rushed 43 times for 146 yards for an average of 3.4 yards per carry. In four, Williams has carried 42 times for 226 yards and three touchdowns. Watkins has caught seven passes for 99 yards and a touchdown in three games.

THE PLAYBOOK: Week 5 preview

- Jeremy Woo

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