Mayo sustained a shoulder injury in Saturday’s divisional round win against the Kansas City Chiefs and did not return to the game.
Mayo, an eight-year NFL veteran, was a part-time starter in the 2015 season after suffering a season-ending injury and undergoing patellar tendon surgery last season. He recorded 47 combined tackles and one sack in eight starts this year for New England.
A first–round selection in the 2008 draft by the Patriots, Mayo has 803 combined tackles, 11.0 sacks, eight forced fumbles and three interceptions over his NFL career.
The Broncos host the Patriots in the AFC Championship Game on Sunday at 3:05 p.m. ET.