Astros vs. Blue Jays Prediction, Odds, Probable Pitchers, Prop Bets for Tuesday, June 23

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Look out for the Toronto Blue Jays. They've fought their way back to .500 at 39-39, and are now starting to get healthy. Shane Bieber is set to make his first start of the 2026 season today when he takes the mound for the Blue Jays.
Let's dive into the odds and my best bets for today's American League showdown.
Astros vs. Blue Jays Odds, Run Line, and Total
Run line
- Astros +1.5 (-194)
- Blue Jays -1.5 (+158)
Moneyline
- Astros +112
- Blue Jays -132
Total
- OVER 8.5 (-115)
- UNDER 8.5 (-105)
Astros vs. Blue Jays Probable Pitchers
- Houston: Peter Lambert, RHP (6-4, 3.23 ERA)
- Toronto: Shane Bieber, RHP (First start of season)
Astros vs. Blue Jays How to Watch
- Date: Tuesday, June 23
- Time: 4:07 p.m. ET
- Venue: Rogers Centre
- How to Watch (TV): Sportsnet, Space City Home Network
- Astros record: 37-43
- Blue Jays record: 39-39
Astros vs. Blue Jays Best MLB Prop Bet
- Vladimir Guerrero Jr. OVER 1.5 Total Bases (+100)
As the Blue Jays start to get hot, so does Vladimir Guerrero Jr. He still needs to find the power he had in last year's postseason, but he has 2+ hits in three of his last five games and has recorded at least one hit in seven of his last nine. Let's bet on him to record at least two bases tonight.
Astros vs. Blue Jays Prediction and Pick
After a rough start to the season, the Blue Jays now rank 14th in the Majors in wRC+ over the past 30 days. Houston's offense hasn't been as good, ranking 19th in that time frame.
The biggest question for today's game is how Bieber will look in his first start of the season, but I have faith in him. He had a 3.57 ERA and a 1.017 WHIP in seven regular-season starts for the Jays last season.
Let's continue to invest in the Jays as they start to look more like the team that made a World Series run last year.
Pick: Blue Jays -132 via FanDuel
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Originally from Nova Scotia, Iain MacMillan is a senior editor covering betting, with a focus on NFL, NHL, and golf. He hosts the Bacon Bets Podcast and has been featured on VSIN, BetQL and Monumental Sports Network. He is a member of the Metropolitan Golf Writers Association and his beloved Falcons and Maple Leafs break his heart on a yearly basis.
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