Cardinals vs. Packers Prediction, Odds, Spread, Trends for NFL Preseason Week 3

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There are a handful of regional rivalries on tap for the final week of the NFL Preseason, but for the Arizona Cardinals vs. Green Bay Packers, we have a brother bowl.
Matt LaFleur of the Packers will face his brother, Mike LaFleur of the Cardinals, in their preseason finale. Mike was hired as the Cardinals' head coach this offseason, so he's getting ready to head into his first regular season as the head honcho.
So far this preseason, the Arizona Cardinals have gone 1-2, losing the Hall of Fame Game to the Carolina Panthers, beating the Las Vegas Raiders, and then losing to the Dallas Cowboys. Meanwhile, the Packers lost to the Pittsburgh Steelers, but then bounced back with a 33-13 win in Denver against the Broncos.
Let's dive into the odds and my best bet for Friday night's game.
Cardinals vs. Packers Odds, Spread, and Total
Odds via DraftKings Sportsbook
Spread
- Cardinals +1.5 (-118)
- Packers -1.5 (-102)
Moneyline
- Cardinals +103
- Packers -123
Total
- OVER 36.5 (-102)
- UNDER 36.5 (-118)
Cardinals vs. Packers How to Watch
- Date: Friday, August 28
- Time: 8:00 p.m. ET
- Venue: Lambeau Field
- How to Watch (TV): Packers TV Network
- Cardinals record: 1-2
- Packers record: 1-1
Cardinals vs. Packers Betting Trends
- Mike LaFleur is 1-2 both straight up and against the spread as a head coach in the preseason
- Matt LaFleur is 10-11 both straight up and against the spread as a head coach in the preseason
Cardinals vs. Packers Key Player to Watch
- Carson Beck, QB - Arizona Cardinals
Carson Beck was extremely impressive in his preseason debut in the Hall of Fame Game, completing 15-of-19 passes for 188 yards and a touchdown. He hasn't played in the Cardinals' two preseason games since due to a rib injury, but he's on track to return to action for the final preseason game. He won't start the season for the Cardinals, but he may be providing a glimpse into their future if he continues to impress.
Cardinals vs. Packers Prediction and Best Bet
Instead of betting on a side in this game, I'm going to bet the OVER in the LaFleur Bowl. Both offenses have been strong so far in the postseason. The Cardinals have hung 30+ points in two of their three games, and the Packers are coming off a 33-point performance against the Broncos, who have one of the best defenses in the NFL.
Quarterbacks for both teams have also been impressive thus far. Gardner Minshew has been great for the Cardinals, and Carson Beck is on track to get back on the field. The 2025 sixth-round pick Kyle McCord has also been good for the Packers. More often than not, good quarterback play is all a game needs to hit the OVER in a preseason affair.
Let's sit back and root for points in this one.
Pick: OVER 36.5 (-102) via DraftKings
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Originally from Nova Scotia, Iain MacMillan is a senior editor covering betting, with a focus on NFL, NHL, and golf. He hosts the Bacon Bets Podcast and has been featured on VSIN, BetQL and Monumental Sports Network. He is a member of the Metropolitan Golf Writers Association and his beloved Falcons and Maple Leafs break his heart on a yearly basis.
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