Cubs vs. Phillies Prediction, Odds, Probable Pitchers, Prop Bets for Wednesday, April 15

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The Philadelphia Phillies host the Chicago Cubs in the rubber match of their three-game set on Wednesday night.
The Phillies took the first game 13-7, but the Cubs gave them a taste of their own medicine with a 10-4 victory last night.
It’s a southpaw showdown in South Philadelphia with Shota Imanaga set to face off against Jesus Luzardo.
Here are the odds, probable pitchers, and predictions for Cubs vs. Phillies on Wednesday, April 15.
Cubs vs. Phillies Odds, Run Line and Total
Odds via DraftKings Sportsbook
Run Line
- Cubs +1.5 (-175)
- Phillies -1.5 (+144)
Moneyline
- Cubs +119
- Phillies -143
Total
- 8.5 (Over -127/Under -102)
Cubs vs. Phillies Probable Pitchers
- Cubs: Shota Imanaga (0-1, 2.81 ERA)
- Phillies: Jesus Luzardo (1-2, 6.23 ERA)
Cubs vs. Phillies How to Watch
- Date: Wednesday, April 15
- Time: 6:40 p.m. ET
- Venue: Citizens Bank Park
- How to Watch (TV): MARQ, NBCSP
- Cubs record: 8-9
- Phillies record: 8-9
Cubs vs. Phillies Best MLB Prop Bets
Phillies Best MLB Prop Bet
- Jesus Luzardo OVER 6.5 Strikeouts (-118)
Jesus Luzardo rediscovered his game last season in Philadelphia. He had a career-high 216 strikeouts in 183.2 IP and a 3.92 ERA across 32 starts.
The southpaw already has 26 strikeouts in 17.1 IP this season, going OVER 6.5 strikeouts in all three starts. Fellow lefthander Cristopher Sanchez had eight strikeouts in six innings of work in the series opener on Monday night.
Cubs vs. Phillies Prediction and Pick
Neither team has found much consistency through the first few weeks of the season, but at least the Cubs won two straight in Tampa Bay last week after dropping the series opener. I could see that same thing playing out tonight in Philadelphia.
While I like Luzardo to rack up the strikeouts, he’s also allowed 12 ER through three starts, including 5 in 4.2 IP against the Diamondbacks last time out. On the flip side, Imanaga threw six hitless innings against the Pirates in his last start.
I’ll back the Cubs as road underdogs tonight in Philly.
Pick: Cubs +119
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Odds refresh periodically and are subject to change.
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Ryan is a sports betting writer at Sports Illustrated. He has experience working for NHL.com, NBC Sports, Covers, and more throughout his decade in the industry. As a Philadelphia native, he understands the passion and pain that come with being a sports fan.
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