Heat vs. 76ers Prediction, Odds and Best NBA Prop Bets for Sunday, Nov. 23

The Miami Heat are coming off a blowout win over the Chicago Bulls in an NBA Cup game on Friday, and they’re looking to carry that momentum into a road date against the Philadelphia 76ers.

Philly knocked off the Milwaukee Bucks (without Giannis) on Thursday to move to 9-6 in the 2025-26 season.

The 76ers are favored by 1.5 points at home in this matchup, but they won’t have Joel Embiid, Kelly Oubre Jr. or Adem Bona on Sunday. Plus, rookie VJ Edgecombe is listed as questionable.

As for the Heat, they have ruled out Tyler Herro, Andrew Wiggins, Nikola Jovic and others for this Eastern Conference clash.

Here’s a breakdown of the odds, my favorite player prop and a prediction for Sunday’s matchup.

Heat vs. 76ers Odds, Spread and Total

Odds via DraftKings Sportsbook.

Spread

Heat +1.5 (-115)
76ers -1.5 (-105)

Moneyline

Heat: -105
76ers: -115

Total

241.5 (Over -108/Under -112)

Heat vs. 76ers How to Watch

Date: Sunday, Nov. 23
Time: 1:00 p.m. EST
Venue: Xfinity Mobile Arena
How to Watch (TV): NBC Sports Philadelphia, FanDuel Sports Network (Local)
Heat record: 10-6
76ers record: 9-6

Heat vs. 76ers Injury Reports

Heat Injury Report

Vladislav Goldin – out
Tyler Herro – out
Kasparas Jakucionis – out
Nikola Jovic – out
Andrew Wiggins – out
Norman Powell – probable
Terry Rozier – out
Dru Smith – available

76ers Injury Report

Joel Embiid – out
Kelly Oubre Jr. – out
VJ Edgecombe – questionable
Jared McCain – available
Adem Bona – out

Heat vs. 76ers Best NBA Prop Bets

Heat Best NBA Prop Bet

Norman Powell OVER 23.5 Points (-113)

Earlier today, I shared in SI Betting’s best NBA props column why Norman Powell is worth a look with multiple Heat rotation players out against Philly:

Powell has gotten off to a terrific start in the 2025-26 season, averaging 24.9 points per game while shooting 49.1 percent from the field and 45.6 percent from beyond the arc.

The veteran shooting guard has picked up the scoring for Miami with Tyler Herro out of the lineup, and both Herro and Andrew Wiggins are sidelined for Sunday’s matchup with the Philadelphia 76ers.

Philly is just 19th in the NBA in defensive rating, which should help Powell and the Heat run their fast-paced attack on Sunday. Powell has seven games with 24 or more points, and I wouldn’t be shocked if he was able to reach his season average again on Sunday.

The Heat star has taken 16.3 shots per game (a career-high) while also getting to the line a career-high 6.4 times per night. He’s worth a shot against a shaky Philly defense that is without Joel Embiid and Kelly Oubre Jr. this afternoon.

Heat vs. 76ers Prediction and Pick

These teams are both in the top half of the NBA in offensive rating this season, and Miami is No. 1 in the league in pace.

That has led to a ton of high-scoring games, as the Heat rank first in the league in points per game (124.8) and 20th in opponent points per game (119.0) this season. The 76ers are a little different, ranking 15th in points per game (118.4) and 16th in opponent points per game (116.1).

Still, I’m expecting a high-scoring affair on Sunday afternoon – even with so many key players out. The Heat have hit the OVER in nine of their 16 games, and they’re combining for nearly 245 points per game this season.

The Sixers are an elite offense when it comes to efficiency (ninth in offensive rating), and I think Tyrese Maxey will thrive in a fast-paced environment on Sunday.

Pick: OVER 241.5 (-108 at DraftKings)

Odds refresh periodically and are subject to change.

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Find Peter Dewey's NBA betting record here (futures included). You can also follow my daily plays on BetStamp here.

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