Michigan vs. Duke Prediction, Odds for College Basketball on Saturday, Feb. 21

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It's rare at this point of the college basketball season to have an out-of-conference game, but it's even more rare for that out-of-conference game to feature two of the top teams in the country. That's exactly what we have on Saturday night when No. 1 Michigan takes on No. 3 Duke at the Capital One Arena in Washington, DC.
Not only is this a must-watch matchup between two of the best teams in the country, but this game's result is going to play a significant role in seeding for next month's NCAA Tournament. It could also end up being a preview of a Final Four or even a National Championship matchup.
Michigan vs. Duke Odds, Spread, and Total
Spread
- Michigan -2.5 (-110)
- Duke +2.5 (-110)
Moneyline
- Michigan -145
- Duke +120
Total
- OVER 148.5 (-110)
- UNDER 148.5 (-110)
Michigan vs. Duke How to Watch
- Date: Saturday, February 21
- Game Time: 6:30 pm ET
- Venue: Capital One Arena
- How to Watch (TV): ESPN
- Michigan Record: 25-1
- Duke Record: 24-2
Michigan vs. Duke Betting Trends
- Michigan is 5-1 ATS in its last six games
- The OVER is 4-2 in Michigan's last six games
- Duke is 8-3 ATS in its last 11 games vs. Michigan
- The UNDER is 6-1 in Duke's last seven games
- Duke is 5-0 ATS in its last five games vs. Big Ten opponents
Michigan vs. Duke Key Player to Watch
- Cameron Boozer, F - Duke Blue Devils
Cameron Boozer is the overwhelming favorite to win the Wooden Award as the nation's best player, but now it's time to see how he can perform against Duke's toughest opponent to date. Boozer leads the Blue Devils in points per game (22.8), rebounds (10.0), assists (3.9), and steals (1.7). Whether or not Duke can win this game will come down to how strong a performance Boozer has.
Michigan vs. Duke Prediction and Pick
There is little to separate these two teams. They rank sixth and 13th in effective field goal percentage and first and third in defensive efficiency. They are also two of the best rebounding teams in the country, while mixing up their offensive play by both attacking the interior and shooting the three-ball.
One area of this game that I think could be the difference maker is turnovers, as it's the one potential weakness that Michigan has. The Wolverines turn the ball over on 16.2% of possessions, which ranks 168th in the country. They also do a bad job of forcing turnovers themselves, ranking 213th in opponent turnovers per possession. By comparison, Duke ranks 116th and 68th in those two metrics.
In a game between two of the best teams in the country, if Duke can win the turnover battle, they're going to have a chance to win this game. I'll take the points with the Blue Devils.
Pick: Duke +2.5 (-110)
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Odds refresh periodically and are subject to change.
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Originally from Nova Scotia, Iain MacMillan is a senior editor covering betting, with a focus on NFL, NHL, and golf. He hosts the Bacon Bets Podcast and has been featured on VSIN, BetQL and Monumental Sports Network. He is a member of the Metropolitan Golf Writers Association and his beloved Falcons and Maple Leafs break his heart on a yearly basis.
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