NFL Straight-Up Moneyline Picks for Every Game in Week 8

Iain MacMillan | Oct 22, 2025

The SI Team Makes their picks for Week 8 / Sports Illustrated

It was a great week of picks from the SI Team! Seven of the eight members of our weekly picks roundtable were profitable in Week 7, with a special shoutout to Peter Dewey, who went 14-1 for +7.12 units with his Week 7 picks!

We're approaching the halfway point of the 2025 NFL season, and while Week 8 has six teams on a bye, there are still 13 games for us to dig into. Let's take a look at everyone's picks for Week 8.

Week 7 Results

• Clare Brennan, Associate Editor 9-6 11-4 (+1.50)
• Mitch Goldich, Senior Editor 13-2 (+5.44 units)
• Gilberto Manzano, NFL Staff Writer 9-6 (-1.31 units)
• Conor Orr, Senior Writer 10-5 (+1.42 units)
• John Pluym, NFL Managing Editor 10-5 (+0.7 units)
• Matt Verderame, NFL Staff Writer 11-4 (+1.25 units)
• Iain MacMillan, Senior Editor, Betting 11-4 (+1.83 units)
• Peter Dewey, Associate Managing Editor, Betting 14-1 (+7.12 units)

Season-to-Date Results

• Clare Brennan, Associate Editor 68-39-1 (-4.37 units)
• Mitch Goldich, Senior Editor 69-37-1 (-1.58 units)
• Gilberto Manzano, NFL Staff Writer 60-57-1 (-14.15 units)
• Conor Orr, Senior Writer 69-38-1 (+5.35 units)
• John Pluym, NFL Managing Editor 66-41-1 (-5.66 units)
• Matt Verderame, NFL Staff Writer 74-33-1 (+7.08 units)
• Iain MacMillan, Senior Editor, Betting 61-46-1 (-8.98 units)
• Peter Dewey, Associate Managing Editor, Betting 68-39-1 (-4.29 units)

NFL Week 8 Picks

All odds are via DraftKings Sportsbook

NFL Week 8 picks / Sports Illustrated

Vikings (+145) vs. Chargers (-175)

• Clare Brennan: Chargers
• Mitch Goldich: Chargers
• Gilberto Manzano: Vikings
• Conor Orr: Chargers
• John Pluym: Chargers
• Matt Verderame: Chargers
• Iain MacMillan: Vikings
• Peter Dewey: Chargers

Dolphins (+285) vs. Falcons (-360)

• Clare Brennan: Falcons
• Mitch Goldich: Falcons
• Gilberto Manzano: Falcons
• Conor Orr: Falcons
• John Pluym: Falcons
• Matt Verderame: Falcons
• Iain MacMillan: Falcons
• Peter Dewey: Falcons

Jets (+240) vs. Bengals (-298)

• Clare Brennan: Bengals
• Mitch Goldich: Bengals
• Gilberto Manzano: Bengals
• Conor Orr: Jets
• John Pluym: Bengals
• Matt Verderame: Bengals
• Iain MacMillan: Jets
• Peter Dewey: Bengals

Browns (+295) vs. Patriots (-375)

• Clare Brennan: Patriots
• Mitch Goldich: Patriots
• Gilberto Manzano: Patriots
• Conor Orr: Patriots
• John Pluym: Patriots
• Matt Verderame: Patriots
• Iain MacMillan: Patriots
• Peter Dewey: Patriots

Giants (+310) vs. Eagles (-395)

• Clare Brennan: Eagles
• Mitch Goldich: Eagles
• Gilberto Manzano: Eagles
• Conor Orr: Eagles
• John Pluym: Eagles
• Matt Verderame: Eagles
• Iain MacMillan: Eagles
• Peter Dewey: Eagles

Bills (-355) vs. Panthers (+280)

• Clare Brennan: Bills
• Mitch Goldich: Bills
• Gilberto Manzano: Bills
• Conor Orr: Bills
• John Pluym: Bills
• Matt Verderame: Bills
• Iain MacMillan: Bills
• Peter Dewey: Bills

Bears (+235) vs. Ravens (-290)

• Clare Brennan: Bears
• Mitch Goldich: Ravens
• Gilberto Manzano: Bears
• Conor Orr: Bears
• John Pluym: Ravens
• Matt Verderame: Bears
• Iain MacMillan: Ravens
• Peter Dewey: Ravens

49ers (-108) vs. Texans (-112)

• Clare Brennan: 49ers
• Mitch Goldich: 49ers
• Gilberto Manzano: 49ers
• Conor Orr: 49ers
• John Pluym: 49ers
• Matt Verderame: 49ers
• Iain MacMillan: Texans
• Peter Dewey: Texans

Buccaneers (-238) vs. Saints (+195)

• Clare Brennan: Buccaneers
• Mitch Goldich: Buccaneers
• Gilberto Manzano: Buccaneers
• Conor Orr: Buccaneers
• John Pluym: Buccaneers
• Matt Verderame: Buccaneers
• Iain MacMillan: Buccaneers
• Peter Dewey: Buccaneers

Cowboys (+150) vs. Broncos (-180)

• Clare Brennan: Broncos
• Mitch Goldich: Broncos
• Gilberto Manzano: Cowboys
• Conor Orr: Broncos
• John Pluym: Cowboys
• Matt Verderame: Cowboys
• Iain MacMillan: Cowboys
• Peter Dewey: Broncos

Titans (+800) vs. Colts (-1350)

• Clare Brennan: Colts
• Mitch Goldich: Colts
• Gilberto Manzano: Colts
• Conor Orr: Colts
• John Pluym: Colts
• Matt Verderame: Colts
• Iain MacMillan: Colts
• Peter Dewey: Colts

Packers (-180) vs. Steelers (+150)

• Clare Brennan: Packers
• Mitch Goldich: Steelers
• Gilberto Manzano: Steelers
• Conor Orr: Steelers
• John Pluym: Packers
• Matt Verderame: Packers
• Iain MacMillan: Packers
• Peter Dewey: Packers

Commanders (+455) vs. Chiefs (-625)

• Clare Brennan: Chiefs
• Mitch Goldich: Chiefs
• Gilberto Manzano: Chiefs
• Conor Orr: Chiefs
• John Pluym: Chiefs
• Matt Verderame: Chiefs
• Iain MacMillan: Chiefs
• Peter Dewey: Chiefs

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