Phillies vs. Marlins Prediction, Odds, Probable Pitchers, Prop Bets for Friday, May 1

In this story:
The Philadelphia Phillies are wheels up to Florida to take on the Miami Marlins after sweeping the Giants at home. It was a much-needed series win, let alone sweep, for the Phillies after firing Rob Thomson.
The Marlins are coming off an impressive series themselves. They blew a late lead in Los Angeles in the series opener before taking down the Dodgers in the last two games.
Here are the odds, probable pitchers, and predictions for Phillies vs. Marlins on Friday, May 1.
Phillies vs. Marlins Odds, Run Line and Total
Odds via DraftKings Sportsbook
Run Line
- Phillies -1.5 (+139)
- Marlins +1.5 (-168)
Moneyline
- Phillies -120
- Marlins +100
Total
- 8 (Over -102/Under -118)
Phillies vs. Marlins Probable Pitchers
- Phillies: Zack Wheeler (0-0, 3.60 ERA)
- Marlins: Eury Perez (2-2, 4.60 ERA)
Zack Wheeler made his first start since last August last week against the Braves, allowing two runs on three hits and three walks while striking out six in five innings of work. He made one start against the Marlins last year, going 7 IP with 5 H, 2 ER, and 13 K in a 7-2 Phillies win.
Eury Perez pitched into the sixth inning last time out, allowing four runs on seven hits in 5.1 innings against the Giants. It was his fourth time allowing four runs in a start this season, although the two times before that included a few unearned runs. The righthander hasn’t pitched against the Phillies since 2023.
Phillies vs. Marlins How to Watch
- Date: Friday, May 1
- Time: 7:10 p.m. ET
- Venue: loanDepot Park
- How to Watch (TV): NBCSP, MIAM
- Phillies record: 12-19
- Marlins record: 15-16
Phillies vs. Marlins Best MLB Prop Bets
Phillies Best MLB Prop Bet
- Zack Wheeler OVER 6.5 Strikeouts (+103)
Wheeler didn’t look unlike himself in his first start in over eight months when he helped the Phillies get a win over the Braves last weekend. Perhaps he was a little limited in his pitch count, as he was pulled after five innings on 84 pitches.
Still, Wheeler struck out six Braves in that one, and now we’re getting plus odds for him to get OVER 6.5 against a Miami team that strikes out more than Atlanta does? I’ll take that, especially after he had 13 strikeouts against the Marlins last season.
Phillies vs. Marlins Prediction and Pick
There aren’t too many times that you’ll see the Phillies as this short of favorites with Wheeler on the mound against an inferior team. Yes, Miami has been better than Philadelphia so far this season, but the Phillies are getting rolling, and they’re due for some positive regression sooner or later.
The Marlins are feeling good after taking two of three in Los Angeles, and that could be their downfall as they host a hungry Phillies team.
I’ll back Philadelphia as slight road favorites in Miami.
Pick: Phillies -120
Register with DraftKings today and get $100 in bonus bets instantly after making a $5 bet. Claim this DraftKings Sportsbook promo code offer by making a $5 deposit and making your first $5 wager.
Odds refresh periodically and are subject to change.
If you or someone you know has a gambling problem and wants help, call 1-800-GAMBLER.

Ryan is a sports betting writer at Sports Illustrated. He has experience working for NHL.com, NBC Sports, Covers, and more throughout his decade in the industry. As a Philadelphia native, he understands the passion and pain that come with being a sports fan.
Follow rgilbertsop