SAN FRANCISCO (AP) Will Venable doubled home the tying runs against Madison Bumgarner and then got himself picked off second on a dribbler to the mound.
He chased the World Series MVP from the game and that might have been his biggest contribution.
Alexi Amarista singled in the go-ahead run and the San Diego Padres beat the San Francisco Giants 3-2 in 11 innings Tuesday night.
''A lot of people did a lot of good things,'' Venable said. ''It wasn't happening for us offensively early in the game.''
Brandon Maurer (5-0) pitched two scoreless innings to earn the victory while Craig Kimbrel earned his 18th save.
Derek Norris doubled against Hunter Strickland (0-1) with one out in the 11th and eventually scored when Amarista's grounder tipped off Strickland's glove and out of the reach of second baseman Joe Panik.
''Bad break there,'' Giants manager Bruce Bochy said. ''That's a tough one to lose. Bum threw so well again. We just couldn't add on.''
Bumgarner retired the first 14 hitters he faced, 10 by strikeout. Brandon Crawford dove to catch Yangervis Solarte's liner just before Yonder Alonso blooped a single into right to break up Bumgarner's bid for a perfect game.
Bumgarner allowed two runs on five hits over 7 1/3 innings. He walked one and struck out a career-high 14.
''I've watched that kid compete,'' Padres manager Pat Murphy said. ''He's as good as there is.''
Gregor Blanco and Panik each drove in runs in the fifth to give the Giants an early edge.
Alonso walked and Will Middlebrooks doubled to open the eighth. After Bumgarner struck out Clint Barmes, Venable delivered.
Odrisamr Despaigne cruised through the first four innings and was seemingly out of the fifth but could not cleanly handle Blanco's slow roller in front of the plate.
He had given up one run in his previous 29 1/3 innings against the Giants. Despaigne allowed two runs on five hits. He walked two and struck out two
Sergio Romo left the game after getting two outs in the top of the ninth with a hyperextended knee.
Padres manager Pat Murphy earned his first career ejection, from home plate umpire Fieldin Culbreth, for arguing balls and strikes in the eighth. Matt Kemp was also ejected.
In all the years he spent coaching at Arizona State, Murphy never once watched a game at AT&T Park, until Tuesday night. He took his son on a tour of Alcatraz Island during Monday's off day and then took a walk around the stadium before the series opener. ''I got to meet Hunter Pence,'' he said. ''That was special. I love the way he plays.'' Murphy coached Giants hitting coach Hensley ''Bam Bam'' Muelens when both were with the 2000 Netherlands team that qualified for the Seoul Olympics. Muelens celebrated his 48th birthday Tuesday.
Padres: Right-hander Brandon Morrow (right shoulder inflammation) is close to throwing a bullpen session or two, which would lead to a simulated game and a possible rehab assignment. ''It doesn't look too far off,'' Murphy said. ... Left-hander Cory Luebke (Tommy John surgery) threw an inning with Double-A San Antonio, giving up a two-run homer. He walked two and struck out two.
Giants: Right-handers Matt Cain (flexor tendon strain) and Jake Peavy (back strain) will each get one more rehab start and will most likely rejoin the Giants on their road trip to Miami and Washington. ... Outfielder Nori Aoki was scratched from the lineup with a fracture in his leg.
Padres: Ian Kennedy (4-5, 5.43) is 2-0 over his last four starts following a four-game losing streak. He's lowered his ERA from 7.15 with a 2.63 ERA during his winning streak.
Giants: Ryan Vogelsong (5-5, 4.38) is coming off one of his best starts of the season, a three-hitter over 6 2-3 innings in a 7-0 win at Seattle. He's still 1-3 over his past four starts, having allowed 12 earned runs over the three losses, a span of 16 1-3 innings