The Nets are resting the 6-foot-11, 253-pound Garnett on second night of back-to-back games.
Cory Jefferson will start for Brooklyn on Saturday night, giving the Nets their sixth different starting in the last six games. He is averaging 3 points and 2.3 rebounds per game.
Garnett, now in his 20th season, is averaging 7.8 points and 8.4 rebounds per game.
Brook Lopez and Miza Teletovic remain out for the Nets.