The Heat expect Wade to be out "for an extended period," Ira Winderman of The Sun-Sentinel reports.
Wade was injured in the third quarter of the 109-102 loss after trying to break through a screen. Wade scored 12 points and had four assists before leaving the game. Wade leads the Heat in scoring (21.4) and assists (5.4) this season.
"I don't have a real definitive update on Wade," Heat head coach Erik Spoelstra told the Sun-Sentinel after the game. "It is a right hamstring strain, don't know how bad it is at this point, right now. We'll know more [Wednesday]."
The injuries continue to pile up for the Heat, which played against Milwaukee without forward Luol Deng (calf) and center Chris Andersen (elbow and back soreness).
“We're bit by something. I don't know if it's a snake," center Chris Bosh said. "We're getting bit by something, and it hurts. It seems like every time we turn the corner, it's a drawback. That's just been the tale of the whole season."
Miami has seven games left before the All-Star break, and play against the Dallas Mavericks on Friday before starting a four-game road trip Sunday in Boston.
The Heat (20-25) are seventh in Eastern Conference standings.
- Scooby Axson