Bosh, 31, was hospitalized last week after having pain in his ribs during the All-Star break. He was diagnosed with blood clots on his lung and ruled out for the rest of the season.
Spoelstra said the team doesn't know when their All-Star power forward will leave the hospital, but "he's getting a little bit better."
NBA commissioner Adam Silver attended the game and gave an interview with Sun Sports about Bosh's health.
''I know it's devastating for him but the great news is this is very treatable, this condition,'' Silver said. ''He's going to be on medication for a while that's going to dictate he can't play for a certain number of months, but he'll be back at full strength.''
In 44 games this season, Bosh averaged 21.1 points, 7.0 rebounds and 2.2 assists while shooting 46.0 percent from the field. He played in his tenth straight All-Star Game last week and also won the Shooting Stars Challenge for the third straight time.
- Paul Palladino