Griffin was injured in the final minute of the fourth quarter of Sunday's 31-28 win over the Baltimore Ravens. The team announced he had a sprained knee. He was scheduled to have an MRI later in the evening.
Griffin tore the ACL in the same knee at Baylor, causing him to miss most of the 2009 college season.
Said Griffin: "I'm not a doctor, but I know what an ACL feels like - and it doesn't feel like an ACL."