Clowney, who was the No. 1 pick in May's draft, is inactive for Sunday's game with an illness. It's the rookie's seventh missed game this season, after he missed six games due to a torn meniscus sustained in Houston's season opener.
According to Rapoport, Clowney did not return from his knee injury as early as the staff thought he would. The linebacker had one tackle in 32 defensive snaps during last week's win over the Titans.
Texans head coach Bill O’Brien was asked Friday if the prospect of Clowney missing another game was frustrating, to which he said no.
"No it's not frustrating at all. Nope, not one bit. It's the National Football League," he told Texans.com.
Clowney was the 2012 SEC Defensive Player of the Year and a 2013 first team All-American while at South Carolina.
The Texans (4-4) are hosting the Eagles (5-2) on Sunday.
- Molly Geary