Colts-Bills Capsule

INDIANAPOLIS (13-6) at BUFFALO (9-7)

Sunday, 1 p.m. ET, CBS

OPENING LINE - Colts by 2 1/2

SERIES RECORD - Bills lead 35-31-1

LAST MEETING - Colts beat Bills 20-13, Nov. 25, 2012

AP PRO32 RANKING - Colts No. 4, Bills No. 19

COLTS OFFENSE - OVERALL (3), RUSH (22), PASS (1)

COLTS DEFENSE - OVERALL (11), RUSH (18), PASS (12)

BILLS OFFENSE - OVERALL (26), RUSH (25), PASS (18)

BILLS DEFENSE - OVERALL (4), RUSH (11), PASS (3)

STREAKS, STATS AND NOTES - The Colts have won seven of the past eight and are 3-1 against former AFC East rival Bills since the NFL realigned divisions in 2002. ... The Colts have lost four of their past five openers, and four straight on the road since beating the Giants 26-21 in 2006. ... With the most yards passing of any quarterback over his first three NFL seasons, Andrew Luck is 43 yards shy of reaching the 13,000 mark. ... RB Frank Gore makes his Colts debut after spending first 10 years in San Francisco. With 11,073 yards rushing, he is 164 yards shy of passing O.J. Simpson for 19th on league list. ... Former Texans WR Andre Johnson also makes his Colts debut, and is 181 yards receiving short of passing Henry Ellard for 11th on NFL list. With 1,012 catches, Johnson needs 13 more to move into eighth, ahead of Isaac Bruce. ... The Colts could welcome back LB Robert Mathis, who was activated from the physically unable to perform list late last month. He is recovering from a torn Achilles tendon. ... The Rex Ryan coaching era begins in Buffalo after the former Jets coach was hired to replace Doug Marrone. ... DT Marcell Dareus will not play while serving a one-game suspension for violating the NFL's substance abuse policy. ... Tyrod Taylor won the Bills offseason quarterback competition and will make his first career start after spending the four years as Joe Flacco's backup in Baltimore. ... RB LeSean McCoy has recovered from a hamstring injury and is set to make his Bills debut. ... Fantasy tip: Expect Luck to target whichever receiver - Johnson or T.Y. Hilton - is matched up against rookie CB Ronald Darby, who is starting in place of Leodis McKelvin (broken ankle). Darby struggled covering PanthersKelvin Benjamin and SteelersMartavis Bryant in preseason.

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