Colts quarterback Jacoby Brissett has been ruled out for Sunday's game against the Dolphins, the team announced on Saturday.
Brissett injured his left knee in last Sunday's game against the Steelers. He exited the game in the second quarter after being hit by his own lineman, Quenton Nelson. The signal-caller dropped to the ground after Nelson was pushed back into his left knee and eventually walked off the field under his own power.
An MRI on Monday confirmed Brissett suffered a sprained MCL, and he was originally listed as questionable for the upcoming game. Brissett was a limited participant in practice this week, taking reps alongside backup QB Brian Hoyer.
Hoyer will get his first start for Indianapolis on Sunday. He entered last week's game after Brissett exited and tallied 168 yards with three touchdowns and an interception in the 26–24 loss.
Indianapolis also moved quarterback Chad Kelly from the practice squad to the active roster ahead of Sunday's game. The Colts will host the Dolphins at Lucas Oil Stadium at 4:05 p.m. ET.