49ers Will be Without Two Key Starters Against the Cardinals

Well this is a bit of a blow to the San Francisco 49ers.

When they face the Arizona Cardinals on Sunday, they will not be at full strength. The 49ers will be without two key starters on the defensive line when they face the Cardinals.

Arik Armstead, who missed the last game against the Seahawks, has been ruled out with a foot/knee injury. Javon Hargrave will join him being inactive for this game as he nurses a pulled hamstring. It shouldn't come as a surprise that either of these players are being held out of this game.

Both of them have missed practice all week, and it especially became evident of them being out when they missed Thursday's practice. Armstead's injuries came up during the Eagles game where he likely toughed it out, thus making his situation worse. But luckily, he and Hargrave do not have anything that appears significant.

The 49ers are taking the cautious route and rightfully so.They need both of them when the playoff run starts to ramp up. Risking them in this game would be silly, especially since they're playing the Cardinals. It shouldn't be that much more difficult to defend against without Armstead and Hargrave.

Besides, the defensive line depth is also adequate with Javon Kinlaw stepping it up along with Kalia Davis giving the 49ers some meaningful snaps. The 49ers should be able to handle the Cardinals without these two key starters.

Here is what the rest of the injury report looks like for the 49ers.

OUT: LB Oren Burks (knee), TE Ross Dwelley (ankle), RB Elijah Mitchell (knee)

QUESTIONABLE: G Aaron Banks (hip), G Spencer Burford (knee), LB Dre Greenlaw (hip, ankle), CB Charvarius Ward (groin)