Five Things to Know About the 49ers 2021 Schedule

The 49ers released their 2021 schedule on Wednesday. Here are five things you should know about it:
1. The 49ers should stay in Youngstown, Ohio between Weeks 1 and 2.
That's because they play in Detroit for the season opener, then in Philadelphia a mere seven days later. If they fly back to San Jose between those games, they'd have to fly more than 9,000 miles in a week, and then they might lose to an Eagles team they absolutely should beat. So the 49ers need to stay in Youngstown, which they probably will.
2. Rookie defensive coordinator DeMeco Ryans will face a big test Week 3 against the Green Bay Packers.
This will be Ryans' third game as a defensive coordinator, and he'll have to face Aaron Rodgers, assuming he's still on the Packers by then. Ryans will have to make key in-game adjustments for the 49ers to win this game, and Ryans might not be ready to make those just yet. Robert Saleh took years to perfect that part of his craft.
3. The 49ers got a unfortunate bye week.
It's Week 6, which means the 49ers will have to play 12 games in a row to finish the season. And then if they make the playoffs, they'll have to play more games in a row, assuming they don't earn the No. 1 seed, which gets a bye week. So it will be extremely difficult, although not impossible, for the 49ers to advance to the Super Bowl.
4. The Thursday Night road game against the Tennessee Titans is a scheduled loss.
That's Week 16. The 49ers will have to fly nearly 2,000 miles to play on just three days of rest to face an established playoffs contender. Usually when the 49ers play road games on Thursday night, they travel short distances, such as Seattle, Phoenix or Los Angeles. Even then, the home team usually wins. Thursday Night football is a joke.
5. The 49ers have the easiest schedule of the NFC West teams.
All four NFC West teams have to play the Packers, Colts, Titans and Vikings, who are are tough opponents. But those are the only quality non-divisional teams the 49ers will face, while the Seahawks have to play Pittsburgh, Washington and New Orleans, the Rams have to play Tampa Bay and Baltimore, and the Cardinals have to play Cleveland and Dallas.
The 49ers should finish 11-6, while the Rams, Seahawks and Cardinals each should finish 9-8.

Grant Cohn has covered the San Francisco 49ers daily since 2011. He spent the first nine years of his career with the Santa Rosa Press Democrat where he wrote the Inside the 49ers blog and covered famous coaches and athletes such as Jim Harbaugh, Colin Kaepernick and Patrick Willis. In 2012, Inside the 49ers won Sports Blog of the Year from the Peninsula Press Club. In 2020, Cohn joined FanNation and began writing All49ers. In addition, he created a YouTube channel which has become the go-to place on YouTube to consume 49ers content. Cohn's channel typically generates roughly 3.5 million viewers per month, while the 49ers' official YouTube channel generates roughly 1.5 million viewers per month. Cohn live streams almost every day and posts videos hourly during the football season. Cohn is committed to asking the questions that 49ers fans want answered, and providing the most honest and interactive coverage in the country. His loyalty is to the reader and the viewer, not the team or any player or coach. Cohn is a new-age multimedia journalist with an old-school mentality, because his father is Lowell Cohn, the legendary sports columnist for the San Francisco Chronicle from 1979 to 1993. The two have a live podcast every Tuesday. Grant Cohn grew up in Oakland and studied English Literature at UCLA from 2006 to 2010. He currently lives in Oakland with his wife.
Follow grantcohn