The Chiefs host the Titans in Week 1 to open each team's NFL regular season. Kansas City started last season 9-0 en route to finishing 11-5 and losing on Wild Card Weekend in the playoffs in head coach Andy Reid's first year. Tennessee finished in second place in the AFC South at 7-9 and replaced head coach Mike Munchak with Ken Whisenhunt this offseason.
Kickoff: 1 p.m. ET
Live stream: The game can be live streamed through NFL Sunday Ticket.
TV coverage: CBS
Kansas City defeated Tennessee 26-17 in Week 5 last season behind four field goals from Ryan Succop, who signed with the Titans earlier this week.
The Chiefs signed quarterback Alex Smith to a four-year, $68 million contract earlier this week.
Smith made the Pro Bowl in his first season with the Chiefs after passing for 3,313 yards and 23 touchdowns.
Last year's playoff berth was the team's first since 2010. Smith set the franchise record for passing yards in a playoff game with 378.
Receiver Dwayne Bowe will not play Sunday as he serves a one-game suspension for violating the league's substance abuse policy.
Offensive tackle Donald Stephenson will not play after being suspended four games for a violation of the league's performance enhancing drugs policy.
In their first season with Reid and Smith, the Chiefs improved from the league's lowest scoring team in 2012 to its sixth best in 2013. The defense improved from 25th in points allowed in 2012 to 5th in 2013.
Running back Jamaal Charles finished last season tied with the Seahawks' Marshawn Lynch for the most rushing touchdowns in the NFL with 12. Charles rushed for 1,287 yards, his fourth 1,000 yard season.
Kansas City drafted Auburn defensive end Dee Ford with the No. 23 pick. Ford had 10.5 sacks and 14.5 tackles for loss during his senior season.
The Chiefs drafted Oregon running back De'Anthony Thomas in the fourth round. The 5-foot-9 Thomas scored ran for 26 touchdowns and and caught another 15 during his college career.
First-year Titans head coach Ken Whisenhunt coached the Arizona Cardinals for six seasons and finished with a 45-51 record, including an appearance in Super Bowl XLIII.
Starting quarterback Jake Locker threw for 1,256 yards, eight touchdowns and four interceptions in seven starts last season.
Running backs Shonn Greene and rookie second-round pick Bishop Sankey will replace Chris Johnson in the backfield after he was released and signed with the New York Jets.
The Titans drafted Michigan tackle Taylor Lewan with the No. 11 pick. He was fined for unnecessary roughness during the preseason.
Tennessee signed former Broncos linebacker Wesley Woodyard to a four-year, $16 million contract. He had 52 tackles, 1.5 sacks and one interception last season.
Cornerback Alterraun Verner signed a four-year, $26.5 million contract with the Tampa Bay Buccaneers. He was third among cornerbacks last season in opposing passer rating at 55.8 and led the team with five interceptions.
Strong safety Bernard Pollard led the team with 77 tackles last season, his first with the team. He also added three interceptions.
Last year marked the fifth straight season Tennessee has failed to qualify for the playoffs. The Titans have not won a playoff game since the 2003 season.
Defensive lineman Jurrell Casey signed a four-year, $36 million contract extension last week.
Locker and Nate Washington were elected captains of the offense, while Woodyard and Casey will captain the defense. George Wilson is the special teams captain.
BONUS: Despite what Madden 15 might say, the Titans do not have an itsy bitsy linebacker.
- Paul Palladino