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Niners-Cardinals Thursday Night Football Betting, Fantasy Preview

San Francisco 49ers at Arizona Cardinals— Thursday, October 31 at 8:20 p.m. EST

Moneyline: SF: (-500) | ARZ: (+385)

Spread: SF: -10 (-110) | ARZ: +10 (-110)

Total: 43 – Over: (-110) | Under: 43 (-110)

Public (Spread) Betting Percentages: SF: 74% | ARZ: 26%

If the sharp action is any indication for what we have in store for Thursday night, all fantasy owners need to start the red-hot Tevin Coleman, star tight end George Kittle, wideout Emmanuel Sanders as well as the San Francisco D/ST with extreme confidence. According to the information provided to Sports Illustrated by Vegas Whispers, the sharps are backing the undefeated 49ers and are laying the double-digit spread (-10). Thursday night’s matchup features two teams going in opposite directions. The 49ers (7-0) have reeled off seven straight wins and currently stand with New England (8-0) as the only two unbeaten teams in the league. The 49ers (7-0 SU, 5-2 ATS) are 3-1 ATS on the road this season. Arizona (3-4 SU, 5-3 ATS) had its three-game SU and ATS winning streak snapped last week when it lost to New Orleans 31-9 as a 13-point underdog.

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San Francisco heads into Thursday night’s game fresh off its most impressive win of the season—a 51-13 dismantling of the Carolina Panthers in Week 8. The 49ers rely upon the league’s most dominant defense as well as a potent running attack led by Coleman. The fifth-year running back was sensational last week with 118 total yards and four touchdowns on just 13 touches. Fantasy owners can once again expect San Francisco’s Kittle, who has 11-plus PPR fantasy points in seven of eight games, to lead the team in targets, receptions and receiving yards against a porous 29th-ranked Arizona defense. San Francisco’s top-ranked defense, led by Nick Bosa, has 18 sacks and nine turnovers over the last four games. On the other side of the ball, fantasy owners should not trust any Arizona players if at all possible.

The line, which opened at San Francisco -8, has seen so much sharp and public action that sportsbooks have been forced to adjust to the line of -10 currently seen all around Vegas. This number will only rise as we get closer to kickoff, so bettors need to get down now! Don't get “tricked” into waiting for a better number just before kickoff and instead get “treated” to the prime number of 10 on Halloween night!

"Trick or Treat" Play: 49ers -10


  • San Francisco is 5-2 ATS in its last seven games overall
  • Arizona is 2-5 ATS in its last seven home games
  • The road team is 5-1 ATS in its last six meetings
  • The under is 4-1 in the last five meetings in Arizona
  • San Francisco is 9-4 ATS in its last 13 meetings in Arizona

Record: 0-2