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NFL Week 15 Odds and Betting Preview

The NFL playoff race is heating up and Week 15 has some exciting games on the schedule.
NFL Week 15 Odds and Betting Preview
NFL Week 15 Odds and Betting Preview

If you haven’t joined in the fun yet, pop on over to SI Sportsbook and put in your free entry today for Week 15. If you pick all 10 of the winners against the spread, you could win up to $10,000.

So, what do you have to lose?

That’s right. Absolutely nothing. Plus, the more picks you make correctly, the more free bets you can earn. Look for our expert picks this Friday as an added bonus.

Here are this week’s lines for SI Sportsbook’s Perfect Ten:

Cowboys at Bills

Dak Prescott reaches a hand out and grabs his chest with the other reacting to a play
Bill Streicher/USA TODAY Sports
  • Contest Line: Cowboys +2.5| Bills -2.5
  • Game Info: Sunday Dec. 17, 4:25 p.m. ET| FOX

These two teams have a lot to play for, and both teams are coming off a big win. Dallas is scoring an average of five more points per game this season, though, and they are tied for the best record in the NFL at 10-3 ATS. Consider taking the points even though the Bills are at home. 

Buccaneers at Packers

  • Game Info: Sunday Dec. 17, 1:00 p.m. ET | FOX

The Buccaneers pulled off the upset win on Sunday, despite the fact I had to look for Mike Evans on a milk carton. Jordan Love and the Packers should be able to exploit this Bucs secondary, though, so choose wisely.

Falcons at Panthers

  • Game Info: Sunday Dec. 17, 1:00 p.m. ET | FOX

The Panthers have covered the spread only once this season. Go ahead and consider buying the hook for the Falcons who are 6-7 ATS.

Jets at Dolphins

Play for Free for the chance to win up to $10,000 on SI Sportsbook

Contest Line: Jets +12.5 | Dolphins -12.5
Game Info: Dec. 17, 1:00 p.m. ET | CBS

Zach Wilson and the Jets put up 30 points at home in the rain on Sunday, upsetting the Houston Texans at MetLife in New York. Going on the road vs. the Dolphins is a different matter, though. Can Wilson keep Aaron Rodgers' playoff hopes alive? SISB thinks not, favoring the Dolphins by -12.5. Miami is 9-3 ATS, and they beat the Jets by a 21 point margin in Week 12 when Tim Boyle was at the helm.

Bears at Browns

  • Game Info: Sunday Dec. 17, 1:00 p.m. ET | FOX

The Bears won outright as underdogs last week, bringing their record to 5-8 ATS this season, but can they keep pace with a 38 year old quarterback straight off the couch? Joe Flacco would say no. Cleveland is 8-5 ATS this year despite the carousel at starting passer.

Giants at Saints

Tommy DeVito and Saquon Barkley
Vincent Carchietta/USA TODAY Sports
  • Game Info: Sunday Dec. 17, 1:00 p.m. ET | FOX

The Saints are still fighting for the NFC South title and should be able to take advantage of this Giants defense.

Texans at Titans

  • Contest Line: Texans +1.5 | Titans -1.5
  • Game Info: Sunday Dec. 17, 1:00 p.m. ET | CBS

If CJ Stroud clears concussion protocol, this line is the steal of the century. If he doesn’t, it’s anyone’s ballgame.

Chiefs at Patriots

Chiefs coach Andy Reid and Patriots coach Bill Belichick have the most wins of any current head coach in the NFL.
David Butler II/USA TODAY Sports
  • Game Info: Sunday Dec. 17, 1:00p.m. ET | FOX

Patrick Mahomes is due for a bounce back game. But, can he bounce-back by a big enough margin? Even Taylor Swift may not have that much influence. The Patriots are only 3-10 vs. the spread this season, while the Chiefs are 8-5.

49ers at Cardinals

  • Game Info: Sunday Dec. 17, 4:05p.m. ET | CBS

The Niners are expected to win big vs. a Cardinals defense that has allowed an average of 25.5 points per game while San Francisco is allowing just 15.5. The Niners are scoring 29.2 points per game while the Cardinals average 17.7. San Francisco is 10-3 ATS this year- tied for the best record with Baltimore, Philadelphia, and Dallas.

Commanders at Rams

  • Game Info: Sunday Dec. 17, 4:05p.m. ET | CBS

The Commanders will be fresh off a bye, but the Rams have looked frisky lately, averaging 34.7 points per game across the last three. The Commanders defense has been the most generous this season, allowing 30.4 points per game to opponents.

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Jennifer Piacenti
JENNIFER PIACENTI

Jennifer Piacenti is a fantasy sports and betting analyst for Sports Illustrated. She serves as a host for Sirius XM Fantasy Sports Radio and has her own podcast, “Waiver Wired,” on the Extra Points podcast network. Piacenti is also a featured expert on MLB Network’s “Bettor’s Eye” and is a member of the esteemed Tout Wars, the fantasy baseball battle of the experts. She is a member of the Fantasy Sports Writers Association and is a 2020 Scott Fish Bowl finalist.

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