Best NFL Picks and Predictions Today for Week 17 (Bet on Eagles to Upset Bills in Buffalo)

Iain MacMillan | 2 Hours Ago

Bet on the Eagles to upset the Bills in NFL Week 17 action. / Bill Streicher-Imagn Images

It's time to grab a cup of coffee, find a spot on the couch, and place your bets for today's NFL action. If you're looking for some bets to tail, look no further. I have something for everyone, including a bet on a favorite, an underdog, and a total. Let's dive into them.

Best NFL Prop Bets Today

Odds via FanDuel Sportsbook

• Steelers vs. Browns UNDER 34.5 (-118)
• Eagles +102 vs. Bills
• 49ers -3 (-116) vs. Bears

Steelers vs. Browns Prediction

The Steelers' offense has been better of late, but now they hit the road to take on one of the best defenses in the NFL, and they'll be without their star receiver, DK Metcalf, who was caught on camera punching a fan against the Lions this past weekend. That could lead to a lackluster offensive performance against the Browns' defense and Myles Garrett, who has a chance to secure the all-time sack record against Aaron Rodgers, who is not nearly as mobile as he was in the prime of his career.

At the same time, I can't trust the Browns' offense at all. Quinshon Judkins is out for the year, and they have no other answer offensively. Shedeur Sanders' numbers are amongst the worst in the league, and he will struggle to move the ball against a solid Pittsburgh defense.

This game has one of the lowest totals in the NFL this season, but that won't scare me away from betting the UNDER.

Pick: UNDER 34.5 (-118)

Eagles vs. Bills Prediction

In the Week 17 edition of the SI Upset Roundtable, I broke down why I think the Eagles are live to upset the Bills:

The Buffalo Bills escaped Cleveland with a win in Week 16, but it was further proof that they're a team with more issues than their record indicates. Their biggest issue is their defense, specifically their complete inability to stop the run. The Bills have allowed a blistering 5.4 yards per carry, the second most in the NFL. They also rank 31st in opponent rush EPA and 27th in opponent rush success rate. Now, they have to take on an Eagles team that is seemingly hitting their stride of late, especially in the run game.

The Eagles have averaged 4.9 yards per carry over their last three games, which has served as a beautiful compliment to a defensive unit that has been one of the best in the league in the second half of the season. Not only are the Eagles a great time to invest in based on how they're playing of late, but the stylistic matchup in this game sways heavily in Philadelphia's favor.

Pick: Eagles +102

Bears vs. 49ers Prediction

In this week's edition of the Road to 272 Bets, I wrote about why I'm backing the 49ers to win and cover against the Bears on Sunday night:

I'm willing to go down with the ship that the Bears aren't a good football team. Another week, another string of unbelievably good luck leading to them winning on the final play of the game. Jordan Love was hurt in the first half, and the Bears still found themselves down 10 points late in the game. A recovered onside kick later, and Chicago was able to force overtime, where they'd eventually win. Despite the win, the Bears are still ranked just 16th in total DVOA, and if you eliminate their takeaways, their defense is in the bottom 10 in virtually every metric.

The 49ers are the better team in most areas, and the Bears' luck is bound to run out sooner or later. I'll take the 49ers as slight home favorites.

Pick: 49ers -3 (-116)

---

Create a new FanDuel Sportsbook account, and you can get $250 in bonus bets if you win your first $5 wager. Download the FanDuel app and deposit a minimum of $5 to claim your FanDuel promo code offer today.

Odds refresh periodically and are subject to change.

If you or someone you know has a gambling problem and wants help, call 1-800-GAMBLER.

You can check out all of Iain's bets here!