Big Ten Conference Prediction, Odds for 2026 College Football Season (Oregon Will Come Out on Top)

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For as long as I can remember, the SEC owned college football, but the Big Ten has made a big statement the past few years, winning three straight national championships.
The Big Ten is once again shaping up to be must-watch football this upcoming college season. Indiana will enter as the defending conference and National Champions, but Ohio State is looking to win the conference for the first time since 2020, and Oregon will try to reclaim the conference title after capturing it in 2024.
Let's dive into the odds to win the Big Ten this season and then I'll break down my prediction.
2026 Big Ten Odds to Win
- Ohio State +180
- Oregon +260
- Indiana +310
- USC +1400
- Michigan +1600
- Penn State +1900
- Washington +3000
- Iowa +4500
- Wisconsin +10000
- UCLA +12500
- Illinois +12500
- Minnesota +12500
- Nebraska +15000
- Northwestern +35000
- Maryland +40000
- Purdue +40000
- Rutgers +40000
- Michigan State +40000
2026 Big Ten Prediction
Predicting that a team besides Ohio State, Oregon, or Indiana to win this year's Big Ten would be a bold claim, and it's not one that I'm willing to make. If you're looking for a team outside the top three, I agree with the betting market in pegging USC as the next most likely option at 14-1. Jayden Maiava is going to be one of the best quarterbacks in the conference, so we know they're going to put up points in bunches. If Gary Patterson, the former TCU head coach, can turn things around on defense, they could end up joining the conversation at the top of the conference.
But let's be realistic. It's going to be one of the three top teams, so I'll start with which team I'm out on, and that's Indiana. Sure, the defending national champions will have another solid squad this season, but they lost a lot of key pieces from last year's team, the downside of building a roster filled with veterans from the transfer portal. Curt Cignetti will likely need a year or two to rebuild for another championship run.
Ohio State is the betting favorite for good reason. Julian Sayin returns as their quarterback, and Jeremiah Smith will once again be one of the best receivers in all of college football. With that being said, returning only three starters on defense is a cause for concern.
That's why my best bet to win the conference is the Oregon Ducks. They have a Heisman contender in Dante Moore, and I'm a big fan of their defensive coordinator, Chris Hampton. People forget that the Ducks allowed just 18.2 points per game last season, one of the best marks in the country. 66% of their total production from last season returns this year, which is the fifth-most in the conference and well above the other two contenders.
Give me the Ducks to win the Big Ten for the second time in three years.
Pick: Oregon to Win Big Ten +260 via FanDuel
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Originally from Nova Scotia, Iain MacMillan is a senior editor covering betting, with a focus on NFL, NHL, and golf. He hosts the Bacon Bets Podcast and has been featured on VSIN, BetQL and Monumental Sports Network. He is a member of the Metropolitan Golf Writers Association and his beloved Falcons and Maple Leafs break his heart on a yearly basis.
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