Lions vs. Colts Prediction, Odds, Spread, Trends for NFL Preseason Week 3

The Colts are favored against the Lions in Week 3 of the NFL Preseason. | IMAGN IMAGES via Reuters Connect

The Detroit Lions and Indianapolis Colts will wrap up their respective preseason schedules against each other on Saturday.

The Lions have played in two low-scoring games so far in the preseason, losing to the Bengals 16-14 and then beating the Commanders 17-13. Meanwhile, the Colts played to a 13-13 tie against the Patriots, and then were steamrolled by the Falcons, 34-6.

Let's dive into the odds and my best bet for this preseason Week 3 showdown.

Lions vs. Colts Odds, Spread, and Total

Odds via DraftKings Sportsbook

Spread

• Lions +3.5 (-108)
• Colts -3.5 (-112)

Moneyline

• Lions +137
• Colts -165

Total

• OVER 35.5 (-110)
• UNDER 35.5 (-110)

Lions vs. Colts How to Watch

• Date: Saturday, August 29
• Time: 1:00 p.m. ET
• Venue: Lucas Oil Stadium
• How to Watch (TV): NFL Network/CBS4/Lions TV Network
• Lions record: 1-1
• Colts record: 0-1-1

Lions vs. Colts Betting Trends

• Dan Campbell is 7-11 straight up and 9-9 against the spread as a head coach in the preseason
• Shane Steichen is 5-5-1 straight up and 5-6 against the spread as a head coach in the preseason

Lions vs. Colts Key Player to Watch

• Anthony Richardson, QB - Indianapolis Colts

Daniel Jones will remain sidelined for this game, and Anthony Richardson will get the start, giving him one more chance to impress and solidify his job as the team's backup. He completed 11-of-14 passes for 145 yards and an interception in Week 1, but he added 53 rushing yards and a touchdown in that game. He was bad in his second game, completing only 3-of-9 passes for 24 yards with three rushes for 15 yards against the Falcons. All eyes will be on him in the Colts' preseason finale.

Lions vs. Colts Prediction and Best Bet

I can't lay points on this Colts team with Anthony Richardson starting at quarterback. He was decent in his first game against the Patriots, but horrific against the Falcons. Now, he has to take on a Lions team that has been great defensively through the first two weeks of the preseason.

The Lions' defensive backups have looked great, which is a great sign for Kelvin Sheppard, the Lions' defensive coordinator, heading into the regular season. With the betting market giving us 3.5 points on the Lions, I'll take those points and hope their defense can keep the game close.

Pick: Lions +3.5 (-108) via DraftKings

---

Follow Iain on X and Instagram

Claim the latest DraftKings promo code offer today. Sign up and get $150 in bonus bets instantly when you make your first $5 bet.

Odds refresh periodically and are subject to change.

If you or someone you know has a gambling problem and wants help, call 1-800-GAMBLER.

You can check out all of Iain's bets here!