Week 5 Fantasy Football Running Back Rankings: Omarion Hampton In The Top 10

Michael Fabiano | Oct 4, 2025

Chargers RB Omarion Hampton (8) has produced at a high level for fantasy managers in the last two weeks. / Vincent Carchietta-Imagn Images

The fifth week of the fantasy football season is here, and with it come the first batch of byes. In fact, nine of the next 10 weeks on the league’s slate will include at least two teams on a bye. This week, the Bears, Falcons Packers, and Steelers are all off the board, so countless managers will need some lineup replacements.

The Week 5 running back rankings have a new player among the top 10, Omarion Hampton, who has broken out in the last two weeks. I also have Cam Skattebo and Quinshon Judkins, two fellow rookies, listed among the top 15 runners.

On the flip side, running backs like Chase Brown, Tony Pollard and Jacory Croskey-Merritt have slipped a bit this week, based on either a bad matchup, poor play or a combination of both scenarios. The same goes for Rhamondre Stevenson.

With that said, here are my complete fantasy football running back rankings for the fifth week of the NFL season.

All Positions: QBs | WRs | TEs | FLEX | Ks | DEFs

Week 5 Fantasy Football RB Rankings

RK	Player	TM	Opponent
1	Christian McCaffrey	SF	at LAR
2	Jahmyr Gibbs	DET	at CIN
3	Jonathan Taylor	IND	vs. LV
4	James Cook	BUF	vs. NE
5	Saquon Barkley	PHI	vs. DEN
6	De'Von Achane	MIA	at CAR
7	Omarion Hampton	LAC	vs. WAS
8	Derrick Henry	BAL	vs. HOU
9	Ashton Jeanty	LV	at IND
10	Breece Hall	NYJ	vs. DAL
11	Kyren Williams	LAR	vs. SF
12	Cam Skattebo	NYG	at NO
13	Rachaad White	TB	at SEA
14	Alvin Kamara	NO	vs. NYG
15	Quinshon Judkins	CLE	vs. MIN
16	Javonte Williams	DAL	at NYJ
17	Travis Etienne Jr.	JAC	vs. KC
18	Kenneth Walker III	SEA	vs. TB
19	Jordan Mason	MIN	at CLE
20	Rico Dowdle	CAR	vs. MIA
21	David Montgomery	DET	at CIN
22	Woody Marks	HOU	at BAL
23	J.K. Dobbins	DEN	at PHI
24	Tony Pollard	TEN	at ARI
25	Nick Chubb	HOU	at BAL
26	Chase Brown	CIN	vs. DET
27	Michael Carter	ARI	vs. TEN
28	TreVeyon Henderson	NE	at BUF
29	Emari Demarcado	ARI	vs. TEN
30	Rhamondre Stevenson	NE	at BUF
31	Zach Charbonnet	SEA	vs. TB
32	Jacory Croskey-Merritt	WAS	at LAC
33	RJ Harvey	DEN	at PHI
34	Isiah Pacheco	KC	at JAC
35	Justice Hill	BAL	vs. HOU
36	Kareem Hunt	KC	at JAC
37	Sean Tucker	TB	at SEA
38	Chris Rodriguez	WAS	at LAC
39	Bhayshul Tuten	JAC	vs. KC
40	Blake Corum	LAR	vs. SF
41	Kendre Miller	NO	vs. NYG
42	Ollie Gordon II	MIA	at CAR
43	Isaiah Davis	NYJ	vs. DAL
44	Tyjae Spears	TEN	at ARI
45	Jaydon Blue	DAL	at NYJ
46	Devin Singletary	NYG	at NO
47	Zavier Scott	MIN	at CLE
48	Ty Johnson	BUF	vs. NE
49	Trevor Etienne	CAR	vs. MIA
50	Brian Robinson Jr.	SF	at LAR
51	Jerome Ford	CLE	vs. MIN
52	Raheem Mostert	LV	at IND
53	Antonio Gibson	NE	at BUF
54	Jeremy McNichols	WAS	at LAC
55	Dylan Sampson	CLE	vs. MIN
56	Ray Davis	BUF	vs. NE
57	Kyle Juszczyk	SF	at LAR
58	Samaje Perine	CIN	vs. DET
59	Brashard Smith	KC	at JAC
60	LeQuint Allen	JAC	vs. KC