It's the first time Parsons has missed a game for the Mavericks since signing a three-year, $46 million offer sheet in the offseason.
The Warriors went into the game with a league-best record of 19-2, and the Mavericks were 0-4 against the teams among the top seven in the Western Conference.
Parsons' back has been sore since he took a hard fall against Memphis on Tuesday. He played a night later against New Orleans.
Parsons had at least 20 points in three straight games before sitting out and is averaging 16.3 points, third on the team.