Top-seeded David Ferrer of Spain began his defense of the Copa Claro title with a comfortable 6-4, 6-1 victory over Argentine wild card Agustin Velotti on Wednesday.
Ferrer, ranked No. 4, is a strong favorite to win his second tournament of the young season. He won in Auckland, New Zealand, last month.
The first-round match was postponed on Tuesday because of rain in the Argentine capital.
Second-seeded Nicolas Almagro of Spain played a second-round match later against Andrey Kuznetsov. Argentines David Nalbandian and Carlos Berlocq also played later in a first-round match.