Bills vs. Browns Prediction, Odds, Spread, Trends for NFL Preseason Week 2

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The Buffalo Bills and Cleveland Browns are set to face each other in Week 2 of the NFL Preseason.
Don't expect starters to be in for many snaps, if any, in this AFC battle. Both coaches have agreed to use their starters for the majority of their joint practice this week, leaving the preseason game on Saturday to largely feature young players and backups.
With that being said, we can still try to find a spot to bet on for this game. Let's dive into it.
Bills vs. Browns Odds, Spread, and Total for Preseason Week 2
Odds via DraftKings Sportsbook
Spread
- Bills +3 (-115)
- Browns -3 (-105)
Moneyline
- Bills +130
- Browns -155
Total
- OVER 37.5 (+105)
- UNDER 37.5 (-125)
Bills vs. Browns How to Watch Preseason Week 2
- Date: Thursday, August 20
- Time: 10:00 p.m. ET
- Venue: SoFi Stadium
- How to Watch (TV): NFL Network, CBS LA, KPIX
- 49ers record: 0-1
- Chargers record: 1-0
Bills vs. Browns Betting Trends
- Joe Brady is 1-0 straight up and against the spread as a head coach in the preseason
- Todd Monken is 0-1 straight up and against the spread as a head coach in the preseason
Bills vs. Browns Key Player to Watch
- Shedeur Sanders, QB - Cleveland Browns
With Deshaun Watson likely sitting for the Browns' preseason game on Saturday, expect Shedeur Sanders to get a significant amount of playing time. His first preseason game didn't go as well as he had hoped, completing 6-of-11 passes for 79 yards and an interception. He'll hope to improve on that mark as the quarterback battle in Cleveland is set to continue throughout the rest of the preseason.
Bills vs. Browns Prediction and Best Bet
I don't think the Browns are deserving of being favorites by a field goal in this game, especially with both teams likely relying on backups throughout the game. I have no faith in any quarterback on the Browns performing at a high level. Meanwhile, Kyle Allen looked solid for the Bills in their first preseason game, completing 14-of-16 passes for 108 yards.
I have more faith in both the Bills' coaching and the depth of their roster to at least keep this game within a field goal.
Pick: Bills +3 (-115) via DraftKings
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Originally from Nova Scotia, Iain MacMillan is a senior editor covering betting, with a focus on NFL, NHL, and golf. He hosts the Bacon Bets Podcast and has been featured on VSIN, BetQL and Monumental Sports Network. He is a member of the Metropolitan Golf Writers Association and his beloved Falcons and Maple Leafs break his heart on a yearly basis.
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