Bills vs. Raiders Prediction, Odds, Spread, Injuries, Trends for NFL Week 6

Josh Allen and the Bills are favored against the Raiders in NFL Week 6 action. | IMAGN IMAGES via Reuters Connect

The Buffalo Bills had their most impressive win of the season on Monday Night Football, beating the Los Angeles Rams in overtime in what could very well be a preview of this season's Super Bowl.

The Bills road trip will continue in Week 6 when they head to Las Vegas to fave the 3-2 Raiders, who have lost two straight games to the Chiefs and Patriots.

Let's dive into the odds and my best bet for this Week 6 AFC showdown.

Bills vs. Raiders Odds, Spread, and Total

Odds via FanDuel Sportsbook

Spread

• Bills -5.5 (-115)
• Raiders +5.5 (-105)

Moneyline

• Bills -275
• Raiders +225

Total

• OVER 53.5 (-110)
• UNDER 53.5 (-110)

Bills vs. Raiders How to Watch

• Date: Sunday, October 18
• Time: 4:25 pm ET
• Venue: Allegiant Stadium
• How to Watch (TV): CBS
• Bills record: 4-1
• Raiders record: 3-2

Bills vs. Raiders Betting Trends

• The OVER is 7-0 in the last seven meetings between these two teams
• Bills are 4-1 against the spread this season
• The OVER is 4-1 in Bills' games this season
• Raiders are 4-1 against the spread this season
• The OVER is 3-2 in Raiders' games this season

Bills vs. Raiders Injury Reports

Bills Injury Report

• Spencer Brown, OT - Questionable
• Landon Jackson, DE - Questionable
• Dee Alford, CB - Questionable
• Joshua Palmer, WR - Questionable

Raiders Injury Report

• Tonka Hemingway, DT - Questionable
• Jalen Nailor, WR - Questioanble
• Trey Zuhn III, C - Questionable
• Patrick Johnson, DE - Questionable
• Dont'e Thornton Jr., WR - IR-R

Bills vs. Raiders Prediction and Best Bet

In the Week 6 edition of the Road to 272 Bets, I broke down why I'm not afraid to lay the points on the Bills:

I think I was right about the Raiders when I picked the Patriots last week. This is a team that got off to a hot start, but not one we should view as legitimate contenders. Their defense is a decent unit, but they still are one of the worst rushing offenses in the league, and since they can't run the ball, they have to rely on Kirk Cousins' arm, which is going to work far less often than it did the first four weeks of the season.

The Raiders' offense won't be able to keep pace with Josh Allen and the Bills' offense. I'm happy to lay the points with the spread set below the magic number of seven.

Pick: Bills -5.5 (-115) via FanDuel

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