College Football National Championship Odds: Florida Makes Major Jump, Oregon, Mississippi State Rise)

Week 4 of the college football season saw several higher seeds fall, as the Penn State Nittany Lions were upset by the Wisconsin Badgers and top-25 teams like Ole Miss and USC both suffered losses that dropped them back in the odds to win the College Football Playoff this season.

The Ohio State Buckeyes remain the favorite this season, but there are six teams at +1000 or less to win it all, making for an exciting regular season ahead.

On Saturday, a few teams made statement wins that altered their odds to win the national title, including the Florida Gators and new head coach Jon Sumrall. Florida was +3300 to win the national title just last week, but a home win over Ole Miss shot the team up to +1800, good for eighth in the latest odds. Ole Miss, on the other hand, dropped back from +1900 all the way t0 +2500.

Arguably the wildest move of the week came after the Oregon Ducks knocked off USC. Oregon star quarterback Dante Moore suffered a scary injury early in the game, and he was replaced by backup Dylan Raiola – a starter previously at Nebraska.

Raiola came in and threw for 289 yards and two scores to lead the Ducks to a win, moving their odds to win the National Championship from +2500 to +2200. It seems like Oregon may be able to weather a Moore injury, even though losing the presumptive first-round pick is certainly not ideal.

In another battle between top-25 teams, Mississippi State and quarterback Kamario Taylor (third in the odds to win the Heisman) took down Missouri and are now +7500 to win the national title, putting them in a small circle of teams with better than +10000 odds.

While the top contenders have mostly remained the same through four weeks, conference play should shake up these odds quite a bit with many ranked teams – especially in the SEC and Big Ten – going head-to-head in the coming weeks.

Here’s a look at the latest odds to win the College Football Playoff in the 2026 season.

College Football National Championship Odds

Odds via FanDuel Sportsbook

Ohio State: +470
Texas: +550
Georgia: +550
Notre Dame: +600
Miami (FL): +700
Indiana: +1000
LSU: +1600
Florida: +1800
Alabama: +2000
Oregon: +2200
Ole Miss: +2500
Tennessee: +4000
Texas Tech: +4500
Mississippi State: +7500

No other team has shorter than 10/1 odds to win the National Championship.

Odds refresh periodically and are subject to change.

If you or someone you know has a gambling problem and wants help, call 1-800-GAMBLER.

Create a new FanDuel Sportsbook account, and you can get up to $1,000 in bonus bets. Register now and make a $5 wager each day for five days to claim your FanDuel promo code offer today.

Add us as a preferred source on Google