Rams vs. Cardinals Prediction, Odds, Spread, Injuries, Trends for NFL Week 10

Carson Beck and the Cardinals are big home underdogs against the Rams in NFL Week 10 action. | IMAGN IMAGES via Reuters Connect

The Los Angeles Rams have strung together three straight wins, but at 5-4, they're still only a coin flip to make the postseason due to a plethora of injuries and a post-BYE schedule that's the hardest in the NFL.

Before they worry about their upcoming gauntlet of tough opponents, they get to take on a severely injured Arizona Cardinals team in Week 10. The Cardinals are down to their No. 3 quarterback, Carson Beck, who will be making his first NFL start.

Let's dive into the odds and my best bet for this divisional duel.

Rams vs. Cardinals Odds, Spread, and Total

Odds via BetMGM Sportsbook

Spread

• Rams -9.5 (-108)
• Cardinals +9.5 (-110)

Moneyline

• Rams -450
• Cardinals +350

Total

• OVER 40 (-108)
• UNDER 40 (-112)

Rams vs. Cardinals How to Watch

• Date: Sunday, November 15
• Time: 4:05 PM ET
• Venue: State Farm Stadium
• How to Watch (TV): CBS
• Rams record: 5-4
• Cardinals record: 3-6

Rams vs. Cardinals Betting Trends

• Rams are 6-4 against the spread in the last 10 meetings between these two teams
• The OVER is 4-2 in the last six meetings between these two teams
• Rams are 3-0 against the spread in their last three games
• The UNDER is 5-4 in Rams games this season
• Cardinals are 4-5 against the spread this season
• The OVER is 5-4 in Cardinals games this season

Rams vs. Cardinals Injury Reports

Rams Injury Report

• Jordan Whittington, WR - Questionable
• Trent McDuffie, CB - Questionable
• Puka Nacua, WR - Doubtful
• Joe Cardona, LS - Questionable
• Terrance Ferguson, TE - IR-R
• Steve Avila, G - Questionable
• Jaylen Watson, CB - Injured Reserve
• Davante Adams, WR - Injured Reserve

Cardinals Injury Report

• Michael Wilson, WR - Out
• James Conner, RB - Injured Reserve
• Jeremiyah Love, RB - Injured Reserve
• Jayden Williams, OT - Questionable
• Bam Knight, RB - Questionable
• Jon Gaines II, G - Questionable
• Hjalte Froholdt, C - Questionable
• Gardner Minshew II, QB - Doubtful

Rams vs. Cardinals Key Player to Watch

• Carson Beck, QB - Arizona Cardinals

Carson Beck, the former Georgia and Miami quarterback, will get his first NFL start this Sunday. He led Miami to the National Championship Game a year ago when he completed 72.4% of passes for 3,813 yards, 30 touchdowns, and 12 interceptions. As a result of his strong senior season, he was selected with the 65th overall pick by the Cardinals in this year's NFL Draft. After a strong preseason, it'll be fascinating to see how he performs on Sunday.

Rams vs. Cardinals Prediction and Best Bet

In this week's edition of the Road to 272 Bets, I broke down why I'm taking the points with the Cardinals:

Both teams are going to be limping into this game. The Rams are going to be down Puka Nacua, which means Tutu Atwell, Jordan Whittington, and Konata Mumpfield will be their starting receivers. Things are even worse for the Cardinals, who traded away Jacoby Brissett last week, and now they've lost Gardner Minshew to an injury, meaning Carson Beck will get his first NFL start. The Cardinals also lost their best wide receiver, Michael Wilson, to injury.

The number of injuries already makes this game tough to handicap, but I continue to be baffled by this Rams team. They managed to win and cover against the Commanders last week, but they had a net yards per play of -0.7. Their special teams are bad and they have been good, but not great on either side of the football.

That, paired with the complete lack of skill they have left at wide receiver, makes me afraid to lay this many points on them on the road. I'll trust the rookie quarterback and take the points with the Cardinals at home.

Pick: Cardinals +9.5 (-110) via BetMGM

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