Reds vs. Diamondbacks Prediction, Odds, Probable Pitchers, Prop Bets for Friday, Aug. 21

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The Arizona Diamondbacks enter Friday sitting one game back of the San Diego Padres for the final spot in the National League playoffs.
They'll face the Cincinnati Reds in a three-game series over the weekend with a chance to close the gap on the Padres. Let's dive into the odds and my best bets for tonight's opener.
Reds vs. Diamondbacks Odds, Run Line, and Total
Run line
- Reds +1.5 (-166)
- Diamondbacks -1.5 (+134)
Moneyline
- Reds +130
- Diamondbacks -140
Total
- OVER 8.5 (-105)
- UNDER 8.5 (-115)
Reds vs. Diamondbacks Probable Pitchers
- Cincinnati: Nick Lodolo, LHP (3-2, 4.52 ERA)
- Arizona: Eduardo Rodriguez, LHP (12-4, 2.71 ERA)
Reds vs. Diamondbacks How to Watch
- Date: Friday, August 21
- Time: 9:40 p.m. ET
- Venue: Chase Field
- How to Watch (TV): DBACKS.TV, Reds.TV
- Reds record: 61-67
- Diamondbacks record: 67-61
Reds vs. Diamondbacks Best MLB Prop Bet
In today's edition of Daily Dinger, I broke down why I'm betting on Corbin Carroll to hit a home run:
Nick Lodolo is another pitcher who has struggled to give up home runs this season. The Reds' pitcher has given up 12 home runs in 14 starts for 1.5 home runs per nine innings pitched. With him being a lefty, we're going to bet on the Diamondbacks' top lefty bat, Corbin Carroll. He has a batting average of .327 and a slugging percentage of .565 when facing left-handed pitchers this season.
Reds vs. Diamondbacks Prediction and Best Bet
The time to bet on the Diamondbacks is when they're facing a left-handed starter. Their offensive numbers skyrocket when facing lefties. For example, their wRC+ this season improves from 89 against right-handed pitchers to 114 against left-handed pitchers.
They'll face a lefty in Nick Lodolo tonight, who has had a less-than-stellar season with a 4.52 ERA. The Diamondbacks have the far better lefty starter Eduardo Rodriguez, and his 2.71 ERA, taking the mound for them.
I'll jump on the Diamondbacks to take care of business tonight.
Pick: Diamondbacks -140 via FanDuel
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Originally from Nova Scotia, Iain MacMillan is a senior editor covering betting, with a focus on NFL, NHL, and golf. He hosts the Bacon Bets Podcast and has been featured on VSIN, BetQL and Monumental Sports Network. He is a member of the Metropolitan Golf Writers Association and his beloved Falcons and Maple Leafs break his heart on a yearly basis.
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