The ACC released its composite men's basketball schedule Wednesday.
Krzyzewski enters this season with 983 career wins. Duke's 17th game is a trip to Louisville on Jan. 17.
The Blue Devils' rivalry games with North Carolina are Feb. 18 in Durham and March 7 in Chapel Hill.
Danny Manning makes his debut at Wake Forest on Nov. 8 against Colgate, and North Carolina State plays 15 of its first 18 games in Raleigh - including visits from Tennessee on Dec. 17 and Cincinnati on Dec. 30.