John Green added 15 points and 10 rebounds for the Gouchos (10-9, 3-2 Big West Conference) and Eric Childress had 11.
After a close first half, Cal State Fullerton pulled ahead on a 10-4 run to end the period with a 36-31 lead.
The Gouchos came back after trailing 40-38 early in the second period on an 8-0 run featuring 3-pointers by Bryson and Mitch Brewe to lead 46-40 with 13:20 to play. The Titans (8-12, 0-5) scored just nine more points in the game after that - and not a single point in the final three minutes - allowing the Gouchos to pull far ahead and cruise to the win.
Lanerryl Johnson led Cal State Fullerton with 21 points. The Titans have now lost five-straight games in conference.