Scott added five rebounds, five assists and three steals to help Indiana State stay undefeated at home in six Missouri Valley Conference games.
Devonte Brown had 12 points, all in the second half, Tre' Bennett added 11 and Justin Gant 10 for Indiana State (11-11, 7-3). Brown, Scott and Bennett hit three 3-pointers apiece.
Indiana State hit four consecutive 3-pointers, two by Bennett, early in the second half to take a 43-37 lead.
Tramique Sutherland led Bradley (7-16, 2-8) with 17 points. Auston Barnes, Josh Cunningham and Anthony Fields had 11 apiece for Bradley.
Both teams shot under 40 percent for the game, but Indiana State held a 41-32 advantage on the glass.