Charlie Lee added 16 points and three rebounds for the Vikings (14-10, 8-2 Horizon League). Trey Lewis had 10 points and Vinny Zollo had nine. The team sank 43.6 percent from the field overall - including 8 of 19 from distance - and 73.9 percent from the free throw line.
Cleveland State led 37-28 at the break and continued to outpace Youngstown State in the second half for the win.
The Penguins (10-16, 1-10) were 24 of 55 from the field overall, including just 4 of 12 (33.3 percent) from beyond the arc.
Shawn Amiker finished with 20 points and 11 rebounds for Youngstown State. Bobby Hain and Osandai Vaughn added 12 points apiece.