Virginiaannounced on Wednesday that sophomore point guard London Perrantes will not play in Wednesday's game at Wake Forest.
Perrantes was listed as day-to-day after sustaining a concussion and broken nose in a collision with teammate Malcolm Brogdon during a win over Florida State on Sunday.
The second-ranked Cavaliers are also playing without guard Justin Anderson, who is recovering from a fractured finger suffered Feb. 7 against Louisville.
Perrantes is averaging 5.9 points, 4.4 assists and 2.3 rebounds per game this season.
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Virginia has won six consecutive games since losing to Duke at home on Jan. 31.
The Cavaliers (25-1, 13-1 ACC) lead the Blue Devils and Notre Dame by two games for first place in the conference standings.