Campbell (5-2) never trailed and built a 13-point lead that Charlotte (1-8) cut to 37-34 by halftime. The Camels led by 10, 59-49, with 11:49 remaining.
Four times in the final 6:30 the 49ers came within one point, the final time on their final basket, a 3-pointer by Andrien White with 3:15 left. But Charlotte missed its last eight shots while Mason made two baskets and Shane Whitfield a free throw for Campbell.
Clemons, a freshman guard, has scored in double figures in all seven Campbell games. Mason added 16 points.
Charlotte dropped its sixth straight. The 49ers had won the previous three games in the series, though the last matchup came in 1983.