The duo combined for 13-of-20 shooting as Harvard made 30 of 47 (64 percent) field-goal attempts. Edosomwan had nine rebounds and five assists, and Cummins blocked four shots.
Patrick Steeves added 12 points for Harvard (6-7) and Tommy McCarthy had 10.
Edosomwan scored eight of Harvard's final 10 points of the first half for a 31-25 lead. He had nine points and eight rebounds in the first 20 minutes.
Tommy McCarthy and Steeves made two 3-pointers during a 9-2 run to extend Harvard's lead to 50-36 midway through the second half. Wofford did not have a run bigger than four points in the second half.
Justin Gordon and C.J. Neumann each had 10 points for Wofford (3-9).